Lab Information

Waqqas Afif (MD/MSc)

Investigator
Clinical Research Unit
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 20%
 Epidemiology: 80%
 Evaluation: 0%
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Keywords

Inflammatory bowel disease • Crohn's disease • ulcerative colitis • biologic medications • therapeutic drug monitoring

Research Interests

My research focuses on the safety and efficiency of biologic medications in the treatment of IBD. I am interested in the use of therapeutic drug monitoring to optimize the treatment of IBD patients on biologic medications.


Team Members

Name Position

Latest Publications

  1. Afif, W., Arasaradnam, R. P., Abreu, M. T., Danese, S., Sandborn, W. J., Miao, Y., Zhang, H., Panaccione, R., Hisamatsu, T., Scherl, E. J., Leong, R. W., Rowbotham, D. S., Peyrin-Biroulet, L., Sands, B. E. & Marano, C. (2024). Efficacy and Safety of Ustekinumab for Ulcerative Colitis Through 4 Years: Final Results of the UNIFI Long-term Maintenance Study. The American journal of gastroenterology.
  2. Wetwittayakhlang, P., Karkout, K., Wongcha-Um, A., Tselekouni, P., Al-Jabri, R., Afif, W., Wild, G., Bitton, A., Bessissow, T. & Lakatos, P. L. (2024). Clinical efficacy and nocebo effect following non-medical biosimilar switch in patients with inflammatory bowel disease: A prospective observational study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 56, p. 35-42.
  3. Gorodensky, J. H., Bernatsky, S., Afif, W., St-Pierre, Y., Filion, K. B. & Vinet, É. (2023). Assessing Serious Infections in Children Exposed In Utero to Ustekinumab. The Journal of rheumatology.
  4. Al-Jabri, R. & Afif, W. (2023). In moderately to severely active UC, etrasimod increased remission at 12 and 52 wk but increased adverse events. Annals of internal medicine, vol. 176, p. JC82.
  5. Gorodensky, J. H., Bernatsky, S., Afif, W., St-Pierre, Y., Filion, K. B. & Vinet, É. (2024). Serious Infections in Offspring Exposed in Utero to Vedolizumab. Inflammatory bowel diseases, vol. 30, p. 496-498.
  6. Wetwittayakhlang, P., Verdon, C., Starr, M., Hahn, G. D., Golovics, P. A., Bessissow, T., Afif, W., Wild, G., Bitton, A. & Lakatos, P. L. (2023). Mucosal Healing and Clinical Efficacy of Adalimumab in Small Intestinal Crohn's Disease (SIMCHA Study): Final Results From a Prospective, Open-Label, Single-Arm Study. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, vol. 34, p. 603-610.
  7. Kablawi, D., Aljohani, F., Palumbo, C. S., Restellini, S., Bitton, A., Wild, G., Afif, W., Lakatos, P. L., Bessissow, T. & Sebastiani, G. (2023). Nonalcoholic Fatty Liver Disease Increases Cardiovascular Risk in Inflammatory Bowel Diseases. Crohn's & colitis 360, vol. 5, p. otad004.
  8. Wetwittayakhlang, P., Golovics, P. A., Khoury, A. A., Ganni, E., Hahn, G. D., Cohen, A., Wyse, J., Bradette, M., Bessissow, T., Afif, W., Wild, G., Bitton, A. & Lakatos, P. L. (2022). Adherence to Objective Therapeutic Monitoring and Outcomes in Patients with Inflammatory Bowel Disease with Adalimumab Treatment. A Real-world Prospective Study. Journal of gastrointestinal and liver diseases : JGLD, vol. 31, p. 403-410.
  9. Heron, V., Li Fraine, S., Panaccione, N., Restellini, S., Germain, P., Candido, K., Bernstein, C. N., Bessissow, T., Bitton, A., Chauhan, U. K., Lakatos, P. L., Marshall, J. K., Michetti, P., Seow, C. H., Rosenfeld, G., Panaccione, R. & Afif, W. (2022). Efficacy of Intravenous Ustekinumab Reinduction in Patients With Crohn's Disease With a Loss of Response. Journal of the Canadian Association of Gastroenterology, vol. 5, p. 208-213.
  10. Hahn, G. D., LeBlanc, J.-F., Golovics, P. A., Wetwittayakhlang, P., Qatomah, A., Wang, A., Boodaghians, L., Liu Chen Kiow, J., Al Ali, M., Wild, G., Afif, W., Bitton, A., Lakatos, P. L. & Bessissow, T. (2022). Effectiveness, safety, and drug sustainability of biologics in elderly patients with inflammatory bowel disease: A retrospective study. World journal of gastroenterology, vol. 28, p. 4823-4833.
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See also

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Talat
Bessissow


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Peter
Lakatos


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Alain
Bitton


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Paul
Brassard


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Évelyne
Vinet


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Sasha
Bernatsky


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