Lab Information

Todd Lee (MD)

Scientist
Clinical Research Unit
Department of Medicine (McGill)

Research Profile

 Fundamental: 30%
 Clinical: 40%
 Epidemiology: 0%
 Evaluation: 30%
 This email address is being protected from spambots. You need JavaScript enabled to view it.
 https://www.drtoddlee.com/

Keywords

Quality improvement • patient safety • high value healthcare • antibiotic stewardship • polypharmacy

Research Interests

My research focuses on conducting randomized clinical trials designed to improve the treatment of infectious diseases (e.g., C. difficile, COVID-19, S. aureus, Gram-Negative infections) and to innovate in the domains of care of complex hospitalized patients, care of older adults with polypharmacy, and stewardship of healthcare resources (e.g., testing, medications).


Team Members

Name Position

Latest Publications

  1. Prosty, C., Bortolussi-Courval, É., Lee, J., Lee, T. C. & McDonald, E. G. (2025). Global Practice Variation in the Management of Clostridioides difficile Infections: An International Cross-Sectional Survey of Clinicians. Open forum infectious diseases, vol. 12, p. ofaf248.
  2. Prosty, C., Noutsios, D., Lee, T. C., Daneman, N., Davis, J. S., Jager, N. G. L., Ghanem-Zoubi, N., Goodman, A. L., Kaasch, A. J., Kouijzer, I., McMullan, B. J., McDonald, E. G., Tong, S. Y. C., Ong, S. W. X. & Staphylococcus aureus Network Adaptive Platform MSSA/PSSA domain specific working group (2025). Cefazolin versus Antistaphylococcal Penicillins for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia: A Systematic Review and Meta-Analysis. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
  3. Ong, S. W. X., Pinto, R., Rishu, A., Tong, S. Y. C., Commons, R. J., Conly, J. M., Evans, G. A., Fralick, M., Kandel, C., Lagacé-Wiens, P. R. S., Lee, T. C., Lother, S. A., MacFadden, D. R., Marshall, J. C., Martel-Laferrière, V., Mayette, M., McDonald, E. G., Neary, J. D., Prazak, J., Raby, E., Regli, A., Rogers, B. A., Smith, S., Taggart, L. R., Wang, H. T., Wuerz, T., Yahav, D., Young, P. J., Fowler, R. A., Daneman, N. & BALANCE trial consortium (2025). Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trial. EClinicalMedicine, vol. 83, p. 103195.
  4. Fresilli, S., Labanca, R., Turi, S., Casuale, V., Vietri, S., Lombardi, G., Covello, R. D., Lee, T. C., Landoni, G., Greco, M. & RIPC group (2025). Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials. British journal of anaesthesia, vol. 134, p. 1373-1384.
  5. Sohani, Z. N., Lieu, A., Semret, M., Cheng, M. P., Simic, N., Bamba, R., Patel, M., Lawandi, A. & Lee, T. C. (2025). Comparison of ciprofloxacin and aminoglycoside susceptibility testing for ceftriaxone non-susceptible Enterobacterales by disk diffusion and VITEK 2 vs. broth microdilution using updated Clinical and Laboratory Standards Institute breakpoints. BMC microbiology, vol. 25, p. 175.
  6. Lee, J. J., Bortolussi-Courval, É., Filosa, E., Rej, S., Godard-Sebillote, C., Tamblyn, R., Lee, T. C. & McDonald, E. G. (2025). Criteria to Report Adverse Drug Withdrawal Events in Clinical Trials: A Systematic Review. Journal of the American Geriatrics Society.
  7. Desormeau, B., Huang, A., Downar, J., Wu, P. E., Bortolussi-Courval, E., Ross, S. B., Battu, K., Papillon-Ferland, L., McAlister, F. A., Elsayed, S., Wilson, M. G., Cavalcanti, R. B., McDonald, E. G. & Lee, T. C. (2025). Prescribing Patterns and Impact of Sedatives in Hospitalized Older Adults: A Secondary Analysis of the MedSafer Study. Journal of the American Geriatrics Society.
  8. Lee, T. C., Prosty, C. J., Fralick, M., Huttner, A., McDonald, E. G., Molina, J., Paul, M., Pinto, R., Rishu, A., von Dach, E., Yahav, D., Fowler, R. & Daneman, N. (2025). Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection: A Systematic Review and Noninferiority Meta-Analysis. JAMA network open, vol. 8, p. e251421.
  9. Prosty, C., Katergi, K., Papenburg, J., Lawandi, A., Lee, T. C., Shi, H., Burnham, P., Swem, L., Routy, B., Yansouni, C. P. & Cheng, M. P. (2024). Causal role of the gut microbiome in certain human diseases: a narrative review. eGastroenterology, vol. 2, p. e100086.
  10. Mahar, R. K., McGlothlin, A., Dymock, M., Barina, L., Bonten, M., Bowen, A., Cheng, M. P., Daneman, N., Goodman, A. L., Lee, T. C., Lewis, R. J., Lumley, T., McLean, A. R. D., McQuilten, Z., Mora, J., Paterson, D. L., Price, D. J., Roberts, J., Snelling, T., Tverring, J., Webb, S. A., Yahav, D., Davis, J. S., Tong, S. Y. C., Marsh, J. A. & SNAP Global Trial Steering Committee (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, vol. 26, p. 49.
More on PubMed 



See also

Card image
Emily
McDonald


See profile
Card image
Matthew
Cheng


See profile
Card image
Alexander
Lawandi


See profile
Card image
Donald
Vinh


See profile
Card image
Cédric
Yansouni


See profile
Card image
Nandini
Dendukuri


See profile