Lab Information

Moshe Ben-Shoshan (MD)

Scientist
Centre for Outcomes Research and Evaluation
Department of Pediatrics (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 20%
 Epidemiology: 80%
 Evaluation: 0%
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Keywords

Food allergy • anaphylaxis • immunodeficiency • chronic urticaria

Research Interests

My research focuses on the prevalence and potential determinants of food allergies and anaphylaxis (severe allergic reactions) in children. In addition, I have established a registry aiming to assess triggers and management of different forms of chronic urticaria, or hives. I also conduct research on primary immunodeficiencies, exploring the ability of children's immune systems to fight infectious disease. In collaboration with Dr. Ann Clarke at the Montreal General Hospital of the MUHC, I conducted the first nationwide Canadian study to determine the prevalence of severe food allergies. The results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates. In recent years I have led the first Canada-wide anaphylaxis registry exploring the societal burden, triggers, management and natural history of anaphylaxis in Canadians.


Team Members

Name Position

Latest Publications

  1. Chu, X., Wang, J., Ologundudu, L., Brignardello-Petersen, R., Guyatt, G. H., Oykhman, P., Bernstein, J. A., Saini, S. S., Beck, L. A., Waserman, S., Moellman, J., Khan, D. A., Ben-Shoshan, M., Baker, D. R., Oliver, E. T., Sheikh, J., Lang, D., Mathur, S. K., Winders, T., Eftekhari, S., Gardner, D. D., Runyon, L., Asiniwasis, R. N., Cole, E. F., Chan, J., Wheeler, K. E., Trayes, K. P., Tran, P. & Chu, D. K. (2024). Efficacy and Safety of Systemic Corticosteroids for Urticaria: A systematic review and meta-analysis of randomized clinical trials. The journal of allergy and clinical immunology. In practice.
  2. Cherrez-Ojeda, I., Bousquet, J., Giménez-Arnau, A., Godse, K., Krasowska, D., Bartosińska, J., Szczepanik-Kułak, P., Wawrzycki, B., Kolkhir, P., Allenova, A., Allenov, A., Tkachenko, S., Teovska Mitrevska, N., Mijakoski, D., Stoleski, S., Kolacinska-Flont, M., Kuprys-Lipinska, I., Molinska, J., Kasperska-Zając, A., Zajac, M., Zamlynski, M., Mihaltan, F., Ulmeanu, R., Zalewska-Janowska, A., Tomaszewska, K., Al-Ahmad, M., Al-Nesf, M. A., Ibrahim, T., Aqel, S., Pesqué, D., Rodríguez-González, M., Wakida-Kuzunoki, G. H., Ramon, G. D., Ramon, G. N., Neisinger, S., Bonnekoh, H., Rukhadze, M., Khoshkhui, M., Fomina, D., Larenas-Linnemann, D., Košnik, M., Oztas Kara, R., Caballero López, C. G., Liu, Q., Ivancevich Juan, C., Ensina, L. F., Rosario, N., Kvedariene, V., Ben-Shoshan, M., Criado, R. F. J., Bauer, A., Cherrez, A., Chong-Neto, H., Rojo-Gutierrez, M. I., Rudenko, M., Larco Sousa, J. I., Lesiak, A., Matos, E., Muñoz, N., Tinoco, I., Moreno, J., Crespo Shijin, C., Hinostroza Logroño, R., Sagñay, J. C., Faytong-Haro, M., Robles-Velasco, K., Zuberbier, T. & Maurer, M. (2024). Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Urticaria are Underused in Clinical Practice. The journal of allergy and clinical immunology. In practice.
  3. Le, M., Khoury, L., Lu, Y., Prosty, C., Cormier, M., Cheng, M. P., Fowler, R., Murthy, S., Tsang, J. L. Y., Ben-Shoshan, M., Rahme, E., Golchi, S., Dendukuri, N., Lee, T. C. & Netchiporouk, E. (2024). COVID-19 Immunologic Antiviral Therapy With Omalizumab (CIAO)-a Randomized Controlled Clinical Trial. Open forum infectious diseases, vol. 11, p. ofae102.
  4. Prosty, C., Alyasin, M., Gabrielli, S., Clarke, A. E., Morris, J., Gravel, J., Lim, R., Chan, E. S., Goldman, R. D., O'Keefe, A., Gerdts, J., Chu, D. K., Upton, J., Hochstadter, E., Moisan, J., Bretholz, A., McCusker, C., Zhang, X., Protudjer, J. L. P., Abrams, E. M., Simons, E. & Ben-Shoshan, M. (2024). Clinical characteristics and management of pediatric egg-induced anaphylaxis: A cross-sectional study. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
  5. Alrafiaah, A. S., Netchiporouk, E. & Ben-Shoshan, M. (2024). Cold-induced anaphylaxis triggered by drinking cold water. Allergologia et immunopathologia, vol. 52, p. 45-47.
  6. Maurer, M., Casale, T. B., Saini, S. S., Ben-Shoshan, M., Giménez-Arnau, A. M., Bernstein, J. A., Yagami, A., Stjepanovic, A., Radin, A., Staudinger, H. W., Patel, N., Amin, N., Akinlade, B., Fan, C., Bauer, D., Yancopoulos, G. D., Patel, K., Mannent, L. P. & Laws, E. (2024). Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): Two randomized, double-blind, placebo-controlled, phase 3 trials. The Journal of allergy and clinical immunology.
  7. Amar, S., Ioia, R. D., Gabrielli, S., Clarke, A. E., Morris, J., Gravel, J., Lim, R., Chan, E. S., Goldman, R. D., O'Keefe, A., Gerdts, J., Chu, D. K., Upton, J., Hochstadter, E., Bretholz, A., McCusker, C., Zhang, X., Protudjer, J. L. P., Simons, E., Abrams, E. M., Colli, M. D., Moisan, J. & Ben-Shoshan, M. (2024). Milk-Induced Anaphylaxis Among Children Presenting to Canadian Emergency Departments. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, vol. 132, p. 512-518.e1.
  8. Barzilai, A., Baum, A., Ben-Shoshan, M., Tzanani, I., Hakroush, R., Coster, D., Solomon, M. & Greenberger, S. (2023). Epidemiological and Clinical Characteristics of Adult and Pediatric Patients with Chronic Spontaneous Urticaria. Journal of clinical medicine, vol. 12.
  9. Mulé, A., Prattico, C., Al Ali, A., Mulé, P. & Ben-Shoshan, M. (2023). Diagnostic and Management Strategies of Food Protein-Induced Enterocolitis Syndrome: Current Perspectives. Pediatric health, medicine and therapeutics, vol. 14, p. 337-345.
  10. Zhu, C. K., Nguyen, A., Prosty, C., Gabrielli, S., Mulé, P., Netchiporouk, E., Le, M., Zhang, X., Shand, G., Baum, S., Hakroush, R., Greenberger, S., Ollech, A., Miedzybrodzki, B. & Ben-Shoshan, M. (2023). Safety of COVID-19 mRNA vaccination and effects of SARS-CoV-2 infection in children and adults with mast cell disorders. Clinical and experimental medicine, vol. 23, p. 4937-4942.
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