Lab Information
Marina Klein (MD/MSc)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
http://www.cocostudy.ca/
Keywords
HIV • Hepatitis C • clinical trials • epidemiology • antiretrovirals • prospective cohortResearch Interests
My research program builds on years of multidisciplinary work leading one of the largest cohorts focused on HIV and hepatitis C virus (HCV) co-infection in the world. As Canada Research Chair in Clinical and Epidemiologic Studies of Chronic Viral Infections in Vulnerable Populations, I am documenting the impact of new HCV therapies on health outcomes, designing and testing tailored approaches to increase access to diagnosis and treatment, building capacity for research with Indigenous communities, and using evidence generated to advocate for policy change. My goal is to pave the way to eliminating HCV and other chronic viral infections in Canada and globally. To this end, I am leading an ambitious project called Montreal Sans Hep C, which aims to make Montreal the first City in North America to eliminate HCV.Team Members
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Latest Publications
- Boateng, N. A., Balasubramaniam, V. M., Pascall, M. A. & Klein, M. S. (2026). Nutrient-induced germination of Bacillus subtilis spores exhibiting shared metabolic profiles in both TSB and AGFK media. Metabolomics : Official journal of the Metabolomic Society, vol. 22.
- Walmsley, S. L., Lovblom, L. E., Boyachuk, B., Cooper, C., Martel-Laferrière, V., Loutfy, M., Vachon, M.-L., Haider, S., Aldebes, P., Colwill, K., Gingras, A. C., Qi, F. & Klein, M. B. (2026). SARS-CoV-2 Infection and COVID-19 Vaccine Antibody Responses in Two Canadian Cohorts of Persons Living with HIV. Antibodies (Basel, Switzerland), vol. 15.
- Young, J., Lawler, P. R., Moodie, E. E. M., Bucher, H. C. & Klein, M. B. (2026). It's about time: The association between abacavir and cardiovascular disease. Antiviral therapy, vol. 31, p. 13596535261438178.
- Young, J., Wang, S., Knight, M., Cardinal, C. L., Cooper, C. L., Cox, J., Hull, M., Martel-Laferriere, V., Sutherland, D. J., Walmsley, S., Wong, A., Klein, M. B. & Canadian Coinfection Cohort (2026). The risk of HIV and HCV transmission in Canadians living with coinfection before, during, and after the COVID pandemic: A prospective cohort study. Canadian journal of public health = Revue canadienne de sante publique.
- Chalouni, M., Torgersen, J., Rentsch, C. T., Van Santen, D. K., Jarrin, I., Klein, M. B., Young, J., Gill, M. J., Epstein, R. L., Linas, B., Zangerle, R., Surial, B., Nemeth, J., Touloumi, G., Papadopoulos, A., Wittkop, L., Van Der Valk, M., Boyd, A., Monforte, A. D., Puoti, M., Logan, R. W., Rein, S. M., Miro, J. M., Berenguer, J., Hernán, M. A. & Lodi, S. (2026). Risk of type 2 diabetes mellitus after treatment with direct-acting antivirals for Hepatitis C virus in people with HIV. AIDS (London, England).
- Lee, J. S., Humes, E., Haw, N. J. L., Hogan, B., Zheng, C., Coburn, S., Lesko, C. R., Lang, R., Gill, M. J., Horberg, M., Silverberg, M. J., Palella, F. J., Delaney, J. A., Rebeiro, P. F., Sterling, T., Rodriguez-Barradas, M., Marconi, V. C., Yendewa, G. A., Klein, M. B., Moore, R., Althoff, K. N. & Research And Design Na-Accord, O. B. O. T. N. A. A. C. C. O. (2026). Harmonizing HIV-1 RNA laboratory measurements in a longitudinal cohort collaboration. American journal of epidemiology.
- Ratevosian, J., Bekker, L.-G., Eakle, R., Baral, S., Cepeda, J., Dugas, L., Dybul, M., Alleyne, G., Eholie, S. P., Esom, K., Grimsrud, A., Havlir, D., Kamarulzaman, A., Kasaie, P., Kazatchkine, M., Kilonzo, N., Klag, M., Klein, M., Lewin, S., Luo, C., Makofane, K., Martin, N., Mayer, K., Millett, G., Ntusi, N., Pace, L., Piot, P., Poniatowski, B., Daskalakis, D., Pozniak, A., Quinn, T., Reynolds, C., Rockstroh, J., Sippel, S., Spire, B., Starrs, A., Strathdee, S., Schechter, M., Thomson, N., Vickerman, P., Weir, B. & Beyrer, C. (2026). Integrating HIV services in an era of global change. Journal of the International AIDS Society, vol. 29, p. e70087.
- Weight, C., Mambro, A., Dussault, C., Chalifoux, S., Del Balso, L., Petropoulos, A., Lim, M., Halavrezos, A., Lebouche, B., Sebastiani, G., Klein, M. B., Cox, J., Latimer, E. & Kronfli, N. (2026). A cost-effectiveness analysis of a multidisciplinary model of care on hepatitis C care among people released from provincial prison in Quebec, Canada. The International journal on drug policy, vol. 149, p. 105136.
- Dushoff, M., Bowdish, D. M. E., Zhabokritsky, A., Lovblom, L. E., Klein, M. B., Boyachuk, B., Falutz, J. M., Loutfy, M., Smith, G. H. R., Tan, D. H. S., Cowbrough, B. & Walmsley, S. L. (2025). A cohort study of growth differentiating factor - 15 (GDF-15) and Interleukin-6 (IL-6) as biomarkers of healthy aging in older adults living with HIV. BMC geriatrics, vol. 26, p. 108.
- Isnard, S., Berini, C. A., Parvathy, S. N., Feng, H., Aiyana, O., Royston, L., Mabanga, T., Lakatos, P. L., Bessissow, T., Klein, M. B., Lebouché, B., Costiniuk, C. T., Routy, B., Silverman, M. S. & Routy, J.-P. (2025). Fecal microbiota transplantation to reduce immune activation in ART-treated people with HIV with low CD4/CD8 ratio: protocol for the single-blind, randomized, placebo-controlled Gutsy study (CIHR/CTN PT038). Trials, vol. 27, p. 52.
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