Lab Information
Elena Netchiporouk (MD/MSc)
ScientistCentre for Translational Biology
Department of Medicine (McGill)
Research Profile
Keywords
Chronic spontaneous urticaria • scleroderma • morphea • systemic sclerosis • skin fibrosisResearch Interests
The incidence of autoimmune diseases affecting the skin and/or internal organs is rising steadily, but at a rate that cannot be explained by genetics alone. This argues for the importance of environmental causes in disease initiation and, possibly, progression. Pollutants and microorganisms (e.g., viruses) may directly damage our cells and elicit production of auto-antibodies by our immune system against our own cells. My research program focuses on understanding the interaction between environment and autoimmune diseases affecting the skin, specifically chronic urticaria and systemic sclerosis. While both are autoimmune in nature, they are completely different with respect to their clinical presentation and prognosis, which makes them ideal to study in parallel.Team Members
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Latest Publications
- Elhaj, H., Al Amari, A., Alyaqout, F., Ben-Shoshan, M., Netchiporouk, E. & Fein, M. (2025). Refractory erythroderma in idiopathic hypereosinophilic syndrome: A case treated with mepolizumab and abrocitinib. SAGE open medical case reports, vol. 13, p. 2050313X251400904.
- Barnawi, G., Bobica, A. C., BinJadeed, H., Ghazal, S. & Netchiporouk, E. (2025). Phosphodiesterase-4 inhibition in localized scleroderma: A case series of topical roflumilast. SAGE open medical case reports, vol. 13, p. 2050313X251406440.
- Kanou, M., Hanna, J., Leclerc, N., Kumarluk, A., Netchiporouk, E. & Litvinov, I. V. (2025). Predominance of Palmoplantar Psoriasis in Inuit Patients from Ungava Bay, Nunavik. Journal of cutaneous medicine and surgery, p. 12034754251404475.
- Khalaf, R., Alsaffar, Z., Alrafiaah, A., Mohamed, S. D., Netchiporouk, E., Fein, M., Sampalis, J. & Ben-Shoshan, M. (2025). Reply to "Anti-TPO antibody, neutrophil, chronic urticaria, and omalizumab". The journal of allergy and clinical immunology. In practice, vol. 13, p. 3453.
- Zhu, C., Peri, K., Silotch, C., Prosty, C., BinJadeed, H., Muntyanu, A., Nagarajan, M., McArthur, P., Benedetti, A. & Netchiporouk, E. (2025). Botulinum Toxin for Refractory Digital Ischemia and Ulcers in Systemic Sclerosis: A Systematic Review and Meta-Analysis. JAMA dermatology.
- Pandey, A. K., Elhaj, H., Nedjar, H., Khoury, L., Rahme, E., Litvinov, I. V., Hundal, S., Kaouache, M. & Netchiporouk, E. (2025). Global burden of major depressive disorder attributable to psoriasis, 2000-2021. Journal of the European Academy of Dermatology and Venereology : JEADV.
- Bendayan, E., Udupa, M., Ouchene, L., Moussa, S., Kaouache, M., Mija, L. A., Chergui, M., Watters, K. A., Marino, T. C., Tanguay, S., Brimo, F., Fu, L., Rahme, E., Foulkes, W. D. & Netchiporouk, E. (2025). Response to Zheng et al. "Advances and Challenges in Diagnostic Strategies for HLRCC-A Letter to the Editor Regarding the Study by Ouchene et al. on HLRCC". Journal of the American Academy of Dermatology.
- Aldien, A. S., Ben-Shoshan, M. & Netchiporouk, E. (2025). Managing chronic spontaneous urticaria. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, vol. 197, p. E1397.
- Moussa, S., Aldien, A. S., Aboushawareb, S. A. E., Sava, R., Netchiporouk, E. & Carver, T. (2025). Dermoscopy Education in Undergraduate Medical Education: Scoping Review of Pedagogical Approaches and Gaps. Journal of medical education and curricular development, vol. 12, p. 23821205251385824.
- Bobica, A. C., Moussa, S., Ouchene, L., Udupa, M., BinJadeed, H., Bashihab, R., Misiewicz, Z., Grönroos, L., Powell, J., Chergui, M., Marino, T. C., Foulkes, W. D. & Netchiporouk, E. (2026). From variant of unknown significance to actionable diagnosis: Stepwise interpretation of a novel KRT2 variant in superficial epidermolytic ichthyosis with excellent retinoid response. JAAD international, vol. 24, p. 16-19.
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