Lab Information
Giada Sebastiani (MD)
ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum fibrosis biomarkers • hepatitis B • hepatitis C • HIVResearch Interests
My research focuses on screening for liver disease and fatty liver of at risk populations, including HIV+ patients, patients with inflammatory bowel disease, liver transplant recipients. To conduct these studies, I employ a non-invasive machine, which is ultrasound based, named Fibroscan. Moreover, I am conducting interventional trials to reduce the fatty liver by vitamin E and switch to less hepatotoxic drugs.Team Members
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Latest Publications
- Guaraldi, G., Milic, J., Renzetti, S., Motta, F., Cinque, F., Bischoff, J., Desilani, A., Conti, J., Medioli, F., Del Monte, M., Kablawi, D., Elgretli, W., Calza, S., Mussini, C., Rockstroh, J. K. & Sebastiani, G. (2024). The effect of weight gain and metabolic dysfunction-associated steatotic liver disease on liver fibrosis progression and regression in people with HIV. AIDS (London, England).
- Douros, A., Cui, Y., Platt, R. W., Filion, K. B., Sebastiani, G. & Renoux, C. (2024). Effectiveness and safety of direct oral anticoagulants among patients with non-valvular atrial fibrillation and liver disease: A multinational cohort study. Thrombosis research, vol. 237, p. 71-78.
- Raggi, P., Milic, J., Manicardi, M., Cinque, F., Swain, M. G., Sebastiani, G. & Guaraldi, G. (2024). Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology. Atherosclerosis, vol. 392, p. 117523.
- Benmassaoud, A., Martel, M., Carli, F., Geraci, O., Daskalopoulou, S. S., Sebastiani, G. & Bessissow, A. (2024). Prehabilitation in patients awaiting liver transplantation. Transplantation reviews (Orlando, Fla.), vol. 38, p. 100835.
- Arora, A. K., Vicente, S., Engler, K., Lessard, D., Huerta, E., Ishak, J., Routy, J.-P., Klein, M., Kronfli, N., Cox, J., Lemire, B., de Pokomandy, A., Del Balso, L., Sebastiani, G., Vedel, I., Quesnel-Vallée, A., ASAP Migrant Advisory Committee & Lebouché, B. (2024). Impact of social determinants of health on time to antiretroviral therapy initiation and HIV viral undetectability for migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite B/F/TAF: 'The ASAP study'. HIV medicine.
- Burnside, J., Thomas, T., Sebastiani, G. & Saeed, S. (2023). Geographical disparities in gastroenterologists and transient elastography across Canada. Canadian liver journal, vol. 6, p. 417-424.
- Zoughlami, A., Serero, J., Congly, S., Zhao, I., Zhu, J., Ramji, A., Cooper, C., Wong, P., Bailey, R., Coffin, C. S., Sebastiani, G. & Canadian HBV Network (2023). Diagnosis of esophageal varices by liver stiffness and serum biomarkers in virus-related compensated advanced chronic liver disease. Canadian liver journal, vol. 6, p. 332-346.
- Feng, G., Valenti, L., Wong, V.-W., Fouad, Y. M., Yilmaz, Y., Kim, W., Sebastiani, G., Younossi, Z. M., Hernandez-Gea, V. & Zheng, M.-H. (2024). Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease. Nature reviews. Gastroenterology & hepatology, vol. 21, p. 46-56.
- Pennisi, G., Enea, M., Romero-Gomez, M., Bugianesi, E., Wai-Sun Wong, V., Fracanzani, A. L., de Ledinghen, V., George, J., Berzigotti, A., Viganò, M., Sebastiani, G., Cannella, R., Delamarre, A., Di Maria, G., Lange, N. F., Tulone, A., Di Marco, V., Cammà, C. & Petta, S. (2024). Risk of liver-related events in metabolic dysfunction-associated steatohepatitis (MASH) patients with fibrosis: A comparative analysis of various risk stratification criteria. Hepatology (Baltimore, Md.), vol. 79, p. 912-925.
- Allameh, A., Niayesh-Mehr, R., Aliarab, A., Sebastiani, G. & Pantopoulos, K. (2023). Oxidative Stress in Liver Pathophysiology and Disease. Antioxidants (Basel, Switzerland), vol. 12.
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